You Do Need power plug adapter while traveling from Cuba to São Tomé and Príncipe.

Here is Why You Need An Adapter

The outlet and plug type used in São Tomé and Príncipe are C and F and in Cuba are A, B, C and L. This is how they look like.

Cuba

In Cuba, outlets of type A, B, C and L are in use.

Type A

Type B

Type C

Type L

São Tomé and Príncipe

In São Tomé and Príncipe, outlets of type C and F are in use.

Type C

Type F