You Do Need power plug adapter while traveling from Tanzania to São Tomé and Príncipe.

Here is Why You Need An Adapter

The outlet and plug type used in São Tomé and Príncipe are C and F and in Tanzania are D and G. This is how they look like.

Tanzania

In Tanzania, outlets of type D and G are in use.

Type D

Type G

São Tomé and Príncipe

In São Tomé and Príncipe, outlets of type C and F are in use.

Type C

Type F